PH3S53 - Advanced Organic Chemistry 01 Aug 2023 - 31 Jul 2029 | Version 8
Associated Module Information
| Module Code: | PH3S53 | ||
|---|---|---|---|
| Module Title: | Advanced Organic Chemistry | ||
| Faculty: | Faculty of Computing, Engineering and Science | ||
| Faculty Group: | Applied Sciences | ||
| Faculty Sub Group: | Chemistry and Pharmaceutical Science | ||
| Module Leader: | Rehana Karim | ||
| Module Team: | Gareth Owen | ||
| First Intended Intake: | SEP 2028 | Final Year of Intake: | 2028 |
| Date Closed: | |||
| Credit Value: | 20 | Credit Level: | 6 |
| Language: | English | ||
| Percentage of Module Taught in Welsh: | 0 | ||
| Equivalent Module: | |||
| HECOS codes: | 100422 - organic chemistry | 101389 - organometallic chemistry | |
| HECOS Code Weighting: | 80 | 20 | |
Document Version Information
| Version | 8 |
|---|---|
| Valid From | 01 Aug 2023 |
| Valid To | 31 Jul 2029 |
Module Aims
To provide the student with an in depth understanding of theory and applications of pericyclic reactions, asymmetric synthesis and transition metals in organic synthesis. On successful completion of this module, students would be able to critically evaluate literature to plan and execute synthesis of compounds of interest in a professional setting.
Content Summary
Pericyclic Reactions
Introduction to pericyclic reactions and FMO theory. Detailed discussion of mechanistic details of electrocyclic reactions, cycloaddition reactions and sigmatropic rearrangements. Application of these reactions in the development of natural products and compounds of interest.
Advanced Stereochemistry
Introduction to stereochemical concepts i.e., chirality and absolute configuration. Methods of generating chiral compounds. Stereochemistry and reactivity of addition, elimination and substitution reactions. Examples of asymmetric synthesis.
Anchimeric Assistance
Introduction to \\\"Neighbouring Group Participation\\\" (NGP). Examples of NGPs. Evaluation of outcomes of NGP assistance for specific reactions.
Homogeneous Catalysis for Organic Synthesis
Fundamental catalytic steps in homogeneous catalysis and their applications with organic synthesis covering examples such as cross-coupling reactions, olefin metathesis and asymmetric catalysis.
Practical work Utilise those skills developed over the past two years to design, plan, safety assess, execute, analyse outcomes in the context of associated literature and write a scientific report on a directed multistep organic synthesis.
Develop new synthesis skills for carrying out a synthesis under a nitrogen atmosphere
Learning and Teaching Methods
| Activity Type | Hours |
|---|---|
| Lecture | 22 |
| Seminar | 14 |
| Practical classes and workshops | 12 |
| Directed Study | 82 |
| Independent Study | 70 |
| Total Hours Selected | 200 |
Learning Outcomes
| # | Learning Outcome |
|---|---|
| LO1 | Rationalise the outcomes of a variety of complex organic reactions by application of principles learned through various topics. |
| LO2 | Critically compare and apply the synthetic methodologies currently available to achieve synthesis of a wide range of organic molecules. Utilise highly specialised technical and theoretical skills to carry out research/laboratory work safely. |
Module Requisites
| Code | Title | Requisite Type |
|---|---|---|
| MOD013091 | Synthetic Organic and Heterocyclic Chemistry | pre-requisite |
Assessment Criteria
| Assessment Category | Assessment Type | Description | Duration | Word Count | Weight (%) | Best of? | Pass Mark |
|---|---|---|---|---|---|---|---|
| Synchronous Onsite Practical Assessment | Practical Coursework (Onsite) 1 | Exercises undertaken in class or in laboratory aimed at assessing the application of knowledge, analytical, problem-solving or evaluative skills. | 0 | 2000 | 50 | No | 40 |
| Asynchronous Assessment | Report 1 | Written assignment allowing demonstration and application of the taught theory of the module. | 0 | 2000 | 50 | 40 |
Assessment Matrix
| Assessment Type | Learning Outcomes | ||
|---|---|---|---|
| LO1 | LO2 | ||
| Practical Coursework (Onsite) 1 | ✔ | ✔ | |
| Report 1 | ✔ | ✔ | |