PH4S005 - Advanced Separation Science 01 Apr 2025 - 31 Aug 2027 | Version 7
Associated Module Information
| Module Code: | PH4S005 | ||
|---|---|---|---|
| Module Title: | Advanced Separation Science | ||
| Faculty: | Faculty of Computing, Engineering and Science | ||
| Faculty Group: | Chemical and Environmental Sciences | ||
| Faculty Sub Group: | Chemical and Environmental Sciences | ||
| Module Leader: | Susanna Kean | ||
| Module Team: | Peter Miedziak, Meirion Pugh, Andrew Graham, Antony Davies | ||
| First Intended Intake: | SEP 2015 | Final Year of Intake: | |
| Date Closed: | |||
| Credit Value: | 20 | Credit Level: | 7 |
| Language: | English | ||
| Percentage of Module Taught in Welsh: | 0 | ||
| Equivalent Module: | |||
| HECOS codes: | 100417 - chemistry | ||
| HECOS Code Weighting: | 100 | ||
Document Version Information
| Version | 7 |
|---|---|
| Valid From | 01 Apr 2025 |
| Valid To | 31 Aug 2027 |
Module Aims
1. To provide students with a detailed theoretical knowledge of a range of advanced separation science methods.
2. To enable students to assess the suitability of specific separation science methods to solve an analytical problem.
3. To allow students to study applications of advanced processes and techniques in pharmaceutical analysis.
Content Summary
Overview of the fundamentals of separation techniques. Focus upon instrumentation, detectors, separation mechanisms/columns. The latest developments will be investigated.
Techniques will include GC, GC-MS, HPLC, LC-MS, MS/MS and UHPLC.
Chiral Chromatography: Methods to achieve a chiral separation such as use of chiral stationary phases (their types and uses) and chiral mobile phase additives.
Advanced Electrophoretic Techniques: Capillary Zone Electrophoresis, Capillary Isoelectric Focussing, Capillary Isotachophoresis, Micellar Electrokinetic Chromatography.
Ion mobility mass spectrometry: theory and practical applications, fast GC/IMS.
Learning and Teaching Methods
| Activity Type | Hours |
|---|---|
| Lecture | 30 |
| Practical classes and workshops | 4 |
| Directed Study | 80 |
| Independent Study | 80 |
| Problem/challenge based learning | 6 |
| Total Hours Selected | 200 |
Learning Outcomes
| # | Learning Outcome |
|---|---|
| LO1 | Display knowledge of advanced separation mechanism, instrumentation and factors which govern resolution and separation quality. |
| LO2 | Select methods and instrument parameters which are suitable for specific applications. |
Module Requisites
N/A
Assessment Criteria
| Assessment Category | Assessment Type | Description | Duration | Word Count | Weight (%) | Best of? | Pass Mark |
|---|---|---|---|---|---|---|---|
| Asynchronous Assessment | Practical Written Work 1 | Submission of an assessment that covers practical instrumentation skills. | 0 | 1000 | 50 | No | 40 |
| Synchronous Online Assessment | Time-constrained assessment (Online) 1 | Students given an online tailored written assignment to complete over a period of 24 h to enable research into topics and application of knowledge | 0 | 2000 | 50 | No | 40 |
Assessment Matrix
| Assessment Type | Learning Outcomes | ||
|---|---|---|---|
| LO1 | LO2 | ||
| Practical Written Work 1 | ✔ | ✔ | |
| Time-constrained assessment (Online) 1 | ✔ | ✔ | |