FP1S35 - Cellular and Molecular Biology 01 Sep 2020 - 31 Aug 2022 | Version 4

Associated Module Information

Module Code: FP1S35
Module Title: Cellular and Molecular Biology
Faculty: Faculty of Computing, Engineering and Science
Faculty Group: Biological and Forensic Sciences
Faculty Sub Group: Biological Science
Module Leader: Paul Jones
Module Team: Deborah Crockard, Jeremy Lewis, Samantha O'Connell, Helen Burn, Hannah Minton
First Intended Intake: AUG 2016 Final Year of Intake:
Date Closed:
Credit Value: 20 Credit Level: 4
Language: English
Percentage of Module Taught in Welsh: 0
Equivalent Module:
HECOS codes: 100388 - forensic science
HECOS Code Weighting: 100

Document Version Information

Version 4
Valid From 01 Sep 2020
Valid To 31 Aug 2022

Module Aims

1. To introduce students to those elements of biology essential for the understanding of its applications in forensic science.

2. To give the student practical laboratory experience in biochemical and microbiological techniques.

Content Summary

Health and Safety: Occupational Health. Physiological anatomy. Toxicology. Occupational ill health and disease. Welfare. The Workplace (Health, Safety and Welfare) Regulations 1992. First Aid. The Health and Safety (First Aid) Regs.
Communication to include Information, Consultation and Safety Signs. Accident Investigation and Reporting. The Reporting of Injuries, Disease and Dangerous Occurrence Regs 1995.
Prokaryotic and Eukaryotic Cell Structure: comparative structure and function in prokaryotic and eukaryotic cells. A review of the major organelles of eukaryotic cells.
Biological Macromolecules: an introduction to structure and function in carbohydrates, lipids, proteins and nucleic acids. Enzyme function and kinetics; factors affecting enzyme activity, enzyme inhibitors.
Fundamentals of Genetics: The role of chromosomes in mitosis and meiosis. An introduction to Mendelian genetics. Principles of population genetics.
Fundamentals of Microbiology: an overview of the important microbial taxonomic groups to include the protozoa, algae, fungi and viruses. An introduction to microbial growth, cultivation and identification.
Cell types: differences in structure eg epithelial cells, secretory cells, nerve cells, muscle cells, specialised plant cells. Tissue sectioning and staining for viewing by light microscope.
The role of bacteria and viruses in forensic science: microorganisms in the decomposition process. The use of microorganisms in bioterrorism. The role of microbes in food poisoning. Protists, fungi and plants as forensic indicators.
The importance of DNA: historical aspects. DNA structure, replication and repair mechanisms. The central dogma; the genetic code, transcription and translation. The molecular basis of mutations; mutagenic agents
Introduction to major organ systems of the body: structure and function of the following systems - muscular, nervous, circulatory, skeletal, digestive systems. Interactions between the systems. Endemiology of cancer in organ systems.
An introduction to the use of bodily fluids and molecular biological techniques as forensic indicators
Practical exercises to include but not be restricted to:
• Calibration and use of the high power light microscope
• Basic microbiological techniques using aseptic techniques
• Determine optimum conditions for enzymic activity
• Slide preparation for cell and tissue examination
• Presumptive tests for bodily fluids
• Isolation of DNA from fruit

Learning and Teaching Methods

Activity Type Hours
Lecture 24
Tutorial 6
Practical classes and workshops 16
Independent Study 106
Directed Study 48
Total Hours Selected 200

Learning Outcomes

# Learning Outcome
LO1 Demonstrate and discuss how cellular and molecular biology is applied to forensic science.
LO2 Understand the cellular and molecular foundation of living things and demonstrate knowledge of the fundamentals of genetics.

Module Requisites

N/A

Assessment Criteria

Assessment Category Assessment Type Description Duration Word Count Weight (%) Best of? Pass Mark
Written Examination Written Examination - Open Book (Unseen) 1 End of module assessment. Open book with an extra 30 minutes provided to students for technical issues with uploading via Turnitin. 60 N/A 25 No 40
Practical Assessment (EX) Practical Examination 1 Practical work (3 experiments) 360 N/A 75 No 40

Assessment Matrix

Assessment Type Learning Outcomes
LO1 LO2
Written Examination - Open Book (Unseen) 1
Practical Examination 1

Reading List

Raven, Johnson, Singer & Losos, Biology. ISBN: 978-1-259-08081-4

Audesirk, Audesirk, Byers, Biology: Life on Earth.

A. Gunn, Essential Forensic Biology.