PE4S156 - Reproductive Endocrinology 01 Sep 2019 - 31 Aug 2031 | Version 2

Associated Module Information

Module Code: PE4S156
Module Title: Reproductive Endocrinology
Faculty: Faculty of Life Sciences and Education
Faculty Group: Allied Health and Chiropractic
Faculty Sub Group: Clinical Services
Module Leader: Karl New
Module Team:
First Intended Intake: SEP 2017 Final Year of Intake: 2030
Date Closed:
Credit Value: 20 Credit Level: 7
Language: English
Percentage of Module Taught in Welsh: 0
Equivalent Module:
HECOS codes: 100260 - healthcare science
HECOS Code Weighting: 100

Document Version Information

Version 2
Valid From 01 Sep 2019
Valid To 31 Aug 2031

Module Aims

Critically evaluate and synthesise current evidence on the presentation, investigation, diagnosis, and management of reproductive endocrine disorders, developing advanced skills in clinical decision-making and patient care strategies.

Content Summary

Indicative content to include topics outlined below and/or any other relevant current topics to fulfil the module aims and learning outcomes:

Topics may include:

Basic physiological principles of the ovaries and testes.

Menstrual cycle

Semen formation

Sex Hormones and variations including SHBG, Testosterone, estradiols, 17OHP, androstenedione and DHEAS

Genetic disorders

Turner syndrome, Klinefelter syndrome, Kallmann syndrome

Polycystic ovarian Syndrome

            Epidemiology

            Investigations

            Diagnostic criteria

Management of associated disorders – hirsutism, oligomennorrhoea and basic fertility treatments.

Medical therapies including metformin, clomiphene, spironolactone. Oral contraceptives and H

Investigation of male and female infertility

Management of the endocrine aspects of male and female infertility

Referral criteria for fertility units

Female hypogonadism

Premature menopause/primary ovarian failure

Menopause

Treatments including Hormone replacement therapy and the OCP

Review of literature relating to HRT and safety

Treatments for associated flushing

Testosterone replacement in postmenopausal females

SERMs

Male hypogonadism

Primary and secondary hypogonadism

Investigations – free testosterone, bioavailable testosterone and total testosterone

Causes including weight-related hypogonadism

Treatments

IM testosterone, testosterone  implants, testosterone gels.

Emerging therapies – SARMs

Monitoring testosterone replacement

Treatment and investigation of erectile dysfunction

PDE-5 inhibitors, vacuum pumps and intracavernosal injections.

Learning and Teaching Methods

Activity Type Hours
Independent Study 80
Directed Study 40
Seminars 40
Problem/Challenge-based Learning 40
Total Hours Selected 200

Learning Outcomes

# Learning Outcome
LO1 Critically evaluate the evidence base and design comprehensive strategies for the investigation, diagnosis, and management of patients with endocrine disorders of the gonads.
LO2 Analyse and critique current approaches to the investigation, diagnosis, and management of endocrine-related fertility issues, proposing innovative solutions where appropriate.

Module Requisites

N/A

Assessment Criteria

Assessment Category Assessment Type Description Duration Word Count Weight (%) Best of? Pass Mark
Synchronous Online Assessment Time-constrained assessment (Online) 1 Assessment to be completed in a specific timescale, which is neither an invigilated examination nor a piece of coursework. To be completed over an extended period (e.g. a 2-hour task to be completed within 48 hours, or a 24-hour assessment). Learna: End of module 1-hour Case-based Multiple-choice Examination related to Reproductive Endocrinology to be completed within a 10-day period. 60 N/A 30 No 40
Asynchronous Assessment Self Reflective Assessment 1 A personal record of a student’s learning experiences. It requires students to record and reflect upon their observations and responses to situations, which can then be used later to explore and analyse ways of thinking and being in context. Generally involves critical diaries, learning logs and written / visual journals. Learna: Reflective journal. 0 600 10 No 40
Asynchronous Assessment Project 1 A detailed analysis of a topic, involving some original research undertaken by the candidate who makes use of data and/or primary sources. Learna: Completion of an individual/group task related to Reproductive Endocrinology. 0 1000 20 No 40
Asynchronous Assessment Case study 1 A concentrated inquiry into a single case or subject. Learna: Case-based scenarios and a discussion forum related to Reproductive Endocrinology. 0 2500 40 No 40

Assessment Matrix

Assessment Type Learning Outcomes
LO1 LO2
Time-constrained assessment (Online) 1
Self Reflective Assessment 1
Project 1
Case study 1

Reading List

The module reading list is available to the students to access via electronic links on the learning platform (Moodle).

In addition to the list below, each list is supplemented with up-to-date peer-reviewed journal articles and studies that are continually refreshed as guidelines change and new treatments and technologies emerge.

Additional reading resources are also provided where relevant by the tutors during the running of the module in the discussion forum to keep the reading resources current and relevant.

Indicative Module 5 Reading:

Androgen Excess and Polycystic Ovary Syndrome Society. [Online]

Androgen Excess and Polycystic Ovary Syndrome Society (no date) Publications. [Online]

Bhasin, S., Brito, J.P., Cunningham, G.R., Hayes, F.J., Hodis, H.N., Matsumoto, A.M., Snyder, P.J., Swerdloff, R.S., Wu, F.C. and Yialamas, M.A. (2018) 'Testosterone Therapy in Men With Hypogonadism: An Endocrine Society Clinical Practice Guideline', The Journal of Clinical Endocrinology & Metabolism, 103(5), pp. 1715-1744.

Clinical Endocrinology. [Online]

Endocrine Reviews. [Online]

Endocrine Society (no date) Clinical Practice Guidelines. [Online]

European Society of Endocrinology (no date) Guidelines. [Online]

Gordon, C.M., Ackerman, K.E., Berga, S.L., Kaplan, J.R., Mastorakos, G., Misra, M., Murad, M.H., Santoro, N.F. and Warren, M.P. (2017) 'Functional Hypothalamic Amenorrhea: An Endocrine Society Clinical Practice Guideline', The Journal of Clinical Endocrinology & Metabolism, 102(5), pp. 1413-1439.

Martin, K.A., Anderson, R.R., Chang, R.J., Ehrmann, D.A., Lobo, R.A., Murad, M.H., Pugeat, M.M. and Rosenfield, R.L. (2018) 'Evaluation and Treatment of Hirsutism in Premenopausal Women: An Endocrine Society Clinical Practice Guideline', The Journal of Clinical Endocrinology & Metabolism, 103(4), pp. 1233-1257.

Society for Endocrinology. [Online]

The Journal of Clinical Endocrinology & Metabolism. [Online]

Wierman, M.E., Arlt, W., Basson, R., Davis, S.R., Miller, K.K., Murad, M.H., Rosner, W. and Santoro, N. (2014) 'Androgen Therapy in Women: A Reappraisal: An Endocrine Society Clinical Practice Guideline', The Journal of Clinical Endocrinology & Metabolism, 99(10), pp. 3489-3510.