PH4S017 - Quality in the Manufacture and Distribution of Medicines 16 Jul 2020 - 31 Aug 2027 | Version 3

Associated Module Information

Module Code: PH4S017
Module Title: Quality in the Manufacture and Distribution of Medicines
Faculty: Faculty of Computing, Engineering and Science
Faculty Group: Chemical and Environmental Sciences
Faculty Sub Group: Chemical and Environmental Sciences
Module Leader: Darren Evans
Module Team: Rehana Karim, Suzanna Kean
First Intended Intake: SEP 2018 Final Year of Intake: 2027
Date Closed:
Credit Value: 20 Credit Level: 7
Language: English
Percentage of Module Taught in Welsh: 0
Equivalent Module:
HECOS codes: 100251 - pharmacy
HECOS Code Weighting: 100

Document Version Information

Version 3
Valid From 16 Jul 2020
Valid To 31 Aug 2027

Module Aims

This module is aimed at personnel working in or wanting to work in the pharmaceutical industry or a related industry. The aim of the module is to provide students with a clear understanding of the underpinning principles, practice and philosophy of Quality and Quality Assurance (QA) through a range of organizational and practical considerations over the whole product life cycle of medicines

Content Summary

The module will examine the underlying principles of Quality Assurance as a key element of quality management systems which underpin the pharmaceutical manufacturing and distribution industries.

Indicative content covered in this module includes:

Industry overview and product lifecycle

Introduction to QMS/QA

The Laboratory – (Basic skills required GLP vs. GMP)

Introduction to GMP – understanding manufacturing systems, packaging, IPC’s, labelling, line clearance and changeover.

Overview of the Orange Guide contents and industry relevance

Introduction to GDP– warehouse management, distribution and delivery, stock control, supply chain management

Compliance– GMP, GCP, health and safety, audits, process performance and product quality monitoring

Process improvement

Continuous improvement

Non-conformities, root cause, CAPA

Change control and management

Quality Risk Management

Product types and manufacturing processes including working in a cleanroom

Introduction to basic environmental monitoring
Clinical trials including blinding and randomisation, GMP/GCP interface

Effective communication

Customer Complaints

Drug Action

Learning and Teaching Methods

Activity Type Hours
Lecture 36
Independent Study 100
Formative Assessment - Independent 64
Total Hours Selected 200

Learning Outcomes

# Learning Outcome
LO1 Critically evaluate the underpinning principles and requirements for Quality Systems/Quality Assurance in the context of working with medicines for human use
LO2 Application of good practice in the development manufacture and wholesale distribution of medicines for human use

Module Requisites

N/A

Assessment Criteria

Assessment Category Assessment Type Description Duration Word Count Weight (%) Best of? Pass Mark
Portfolio Portfolio 1 Scenario based problem solving based on the application of good practice in industry 0 2000 35 No 40
Written Assignment (CW) Report (CW) 1 Completion of a professional style report based on the application of one or more industry related processes linked to a real life scenario. 0 3900 65 No 40

Assessment Matrix

Assessment Type Learning Outcomes
LO1 LO2
Portfolio 1
Report (CW) 1

Reading List

‘Rules and Guidance for Pharmaceutical Manufacturers and Distributors 2015’ (‘The Orange Guide’) by The Medicines and Healthcare products Regulatory Agency, Pharmaceutical Press ISBN 978 085369 719 0ISO9000:2005

Quality in the Manufacture of Medicines and other healthcare products by John Sharp;Second
Edition 2011 (PHSS) ISBN 978-1-905271-21-4

Rules and Guidance for Pharmaceutical Distributors 2015 (The Green Guide), by MHRA (Medicines and Healthcare products Regulatory Agency) 2015