PH3S108 - Regulations for the Manufacture of Combination & Device Products 01 Jan 2022 - 31 Aug 2028 | Version 1

Associated Module Information

Module Code: PH3S108
Module Title: Regulations for the Manufacture of Combination & Device Products
Faculty: Faculty of Computing, Engineering and Science
Faculty Group: Applied Sciences
Faculty Sub Group: Chemistry and Pharmaceutical Science
Module Leader:
Module Team: Suzanna Kean
First Intended Intake: Final Year of Intake:
Date Closed:
Credit Value: 20 Credit Level: 6
Language: English
Percentage of Module Taught in Welsh: 0
Equivalent Module:
HECOS codes: 100078 - business and management 100144 - pharmaceutical engineering 100185 - safety engineering
HECOS Code Weighting: 35 35 30

Document Version Information

Version 1
Valid From 01 Jan 2022
Valid To 31 Aug 2028

Module Aims

The aim of the module is to give students a broad understanding of the regulations underpinning the manufacture of safe combination and device products for the public, including the regulatory environment for combination products and medical devices, and the Quality Management System (QMS) necessary for the reliable delivery of high-quality products across a selection of manufacturing technologies.

Content Summary

The module will explore:

• The regulatory environment for combination products and medical devices

• The key elements of a robust Quality Management System (QMS) necessary for the reliable delivery of high quality products

• The Fundamentals of validation for combination products

• An introduction to selected manufacturing technologies involved in the manufacture of combination and device products

Indicative Syllabus:

• Overview of Combination Products & Medical Device Regulations (US,EU, ISO13485, etc).

• Navigating the Design, Design Control, Design Verification Process

• Quality Management Systems including Effective Change Management, Proactive CAPA management

• Verification versus Validation in Med Tech sector – including; Applying Risk Management to the Validation Process

• Supply Chain Management – The importance of building successful supplier partnerships and the role of supplier qualification, auditing and purchasing controls.

This module is delivered through open/distance learning resource packs, pre-recorded lectures, problem-solving exercises and case studies.

Learning and Teaching Methods

Activity Type Hours
Independent Study 100
Directed Study 86
Formative Assessment - Independent 14
Total Hours Selected 200

Learning Outcomes

# Learning Outcome
LO1 Demonstrate an understanding of current regulatory environment for the manufacture of combination products and medical devices
LO2 Understand the key principles involved in the validation of and the QMS specific to the manufacture of combination products and medical devices.
LO3 Demonstrate an understanding of some of the key technologies used in the manufacture of these products and the challenges associated with them.

Module Requisites

N/A

Assessment Criteria

Assessment Category Assessment Type Description Duration Word Count Weight (%) Best of? Pass Mark
Asynchronous Assessment Self Reflective Assessment 1 Self reflection by the student on their academic journey to date 0 400 10 No 40
Asynchronous Assessment Report 2 Assignment case study to address the validation of a combination product or medical device product. 0 3000 30 No 40
Asynchronous Assessment Report 1 Assignment to demonstrate understanding of the regulations relating to a combination product or medical device product. 0 1800 30 No 40
Synchronous Online Assessment (Exam) Online Open Book Examination (Not Proctored) 1 Open book exam consisting of a series of short questions on the module content 180 N/A 30 No 40

Assessment Matrix

Assessment Type Learning Outcomes
LO1 LO2 LO3
Self Reflective Assessment 1
Report 2
Report 1
Online Open Book Examination (Not Proctored) 1

Reading List

Open distance/learning pack of materials resources

AUTHOR: Culjat, Martin, Medical devices : surgical and image guided technologies, CALL NO: 610.284 CUL, BARCODE: 33333013119199

AUTHOR: FDAnews, Guide to international Medical Device Regulation, CALL NO: 610.284 FDA, BARCODE: 33333013008467