PE4S263 - Physiology and Pathophysiology of Calcium Homeostasis and Bone Metabolism 01 Sep 2024 - 31 Aug 2030 | Version 2

Associated Module Information

Module Code: PE4S263
Module Title: Physiology and Pathophysiology of Calcium Homeostasis and Bone Metabolism
Faculty: Faculty of Life Sciences and Education
Faculty Group: Health, Sport and Professional Practice
Faculty Sub Group: Clinical Services
Module Leader:
Module Team: Ishrat Khan, Preethi Nalla, Satinath Mukhopadhyay, Samuel Mucheru, Som Lakhani, Paul Grant, Tamseela Ahmed, Haseena Hamdani, Ashleigh Horn, Vikas Mital
First Intended Intake: SEP 2024 Final Year of Intake:
Date Closed:
Credit Value: 20 Credit Level: 7
Language: English
Percentage of Module Taught in Welsh: 0
Equivalent Module:
HECOS codes: 100260 - healthcare science
HECOS Code Weighting: 100

Document Version Information

Version 2
Valid From 01 Sep 2024
Valid To 31 Aug 2030

Module Aims

This module aims to provide healthcare professionals with an in-depth understanding of the physiological and pathophysiological mechanisms involved in calcium
homeostasis and bone metabolism.

Content Summary

Indicative content to include topics outlined below and/or
any other relevant current topics to fulfil the module aims and learning outcomes:
? Normal calcium homeostasis
? Vitamin D physiology and supplementation
? Phosphate homeostasis and disorders
? Magnesium regulation and disorders
? Bone physiology and role of diet
? Role of gonadal steroids and growth hormone in bone health

Learning and Teaching Methods

Activity Type Hours
Independent Study 100
Directed Study 100
Total Hours Selected 200

Learning Outcomes

# Learning Outcome
LO1 An ability to critically analyse and interpret the evidence base related to the process of calcium homeostasis and the role of various hormones and regulatory mechanisms in maintaining normal calcium levels in the body.
LO2 Critically evaluate the evidence relating to the physiology and pathophysiology of calcium homeostasis and bone metabolism and relate the learning into clinical practice.

Module Requisites

N/A

Assessment Criteria

Assessment Category Assessment Type Description Duration Word Count Weight (%) Best of? Pass Mark
Synchronous Online Assessment Time-constrained assessment (Online) 1 Assessment to be completed in a specific timescale, which is neither an invigilated examination nor a piece of coursework. To be completed over an extended period (e.g. a 2-hour task to be completed within 48 hours, or a 24-hour assessment).Lear na: End of module, 1-hour MCQ examination related to Physiology and Pathophysiology of Calcium Homeostasis and Bone Metabolism, to be completed within a 10-day period. 60 600 30 No 40
Asynchronous Assessment Self Reflective Assessment 1 A personal record of a student’s learning experiences. It requires students to record and reflect upon their observations and responses to situations, which can then be used later to explore and analyse ways of thinking and being in context. Generally involves critical diaries, learning logs and written / visual journals. Learna Reflective journal 0 600 10 No 40
Asynchronous Assessment Project 1 A detailed analysis of a topic, involving some original research undertaken by the candidate who makes use of data and/or primary sources. Learna Completion of an individual/group task related to the physiology and pathophysiology of calcium homeostasis and bone metabolism. 0 1000 20 No 40
Asynchronous Assessment Case study 1 A concentrated inquiry into a single case or subject. Learna Case-based scenarios and discussion forum related to the physiology and pathophysiology of calcium homeostasis and bone metabolism. 0 2400 40 No 40

Assessment Matrix

Assessment Type Learning Outcomes
LO1 LO2
Time-constrained assessment (Online) 1
Self Reflective Assessment 1
Project 1
Case study 1

Reading List

Core:
Shaker, J.L. and Deftos, L., 2023. Calcium and phosphate homeostasis. Endotext [Internet].
Available at: https://www.ncbi.nlm.nih.gov/books/NBK279023/

 

Journals:

Journal of Bone and Mineral Research (nd). Available at: https://www.asbmr.org/Publications/jbmr

Nho, J.H., Jang, B.W., Lee, D.W., Kim, J.H., Lim, T.K., Cha, S.M., Seo, D.K., Park, Y.G., Kang,
D.G., Lee, Y.K. and Ha, Y.C., (2023). Position Statement: Atypical Femoral Fracture from the Korean Society for Bone and Mineral Research in 2023. Journal of Bone Metabolism, 30(3), pp.209-217. Available at: https://www.e-jbm.org/upload/pdf/jbm-2023-30-3-209.pdf

Peacock, M., (2010). Calcium metabolism in health and disease. Clinical Journal of the American society of nephrology, 5(Supplement_1), pp.S23-S30. Available at: https://journals.lww.com/cjasn/fulltext/2010/01001/calcium_metabolism_in_health_and_diseas e.4.aspx

Articles:

Bouillon, R., Manousaki, D., Rosen, C., Trajanoska, K., Rivadeneira, F. and Richards, J.B., (2022). The health effects of vitamin D supplementation: Evidence from human studies. Nature Reviews Endocrinology, 18(2), pp.96-110. Available at: https://www.nature.com/articles/s41574-021-00593-z

Cormick, G. and Belizán, J.M., (2019). Calcium intake and health. Nutrients, 11(7), p.1606. Available at: https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6683260/

Veldurthy, V., Wei, R., Oz, L., Dhawan, P., Jeon, Y.H. and Christakos, S., 2016. Vitamin D, calcium homeostasis and aging. Bone research, 4(1), pp.1-7. Available at: https://www.nature.com/articles/boneres201641