7B021B - Cellular and Molecular Basis of Disease 01 Sep 2027 - 31 Aug 2033 | Version 0

Associated Module Information

Module Code: 7B021B
Module Title: Cellular and Molecular Basis of Disease
Faculty: Faculty of Computing, Engineering and Science
Faculty Group: Applied Science
Faculty Sub Group: Biology and Chemistry
Module Leader: Sioned Owen
Module Team: Martin Powell, Aled Bryant, Lewis Fall, Josephine Bradley
First Intended Intake: SEP 2027 Final Year of Intake: 2032
Date Closed:
Credit Value: 30 Credit Level: 7
Language: English
Percentage of Module Taught in Welsh: 33
Equivalent Module:
HECOS codes: 100265 - biomedical sciences
HECOS Code Weighting: 100

Document Version Information

Version 0
Valid From 01 Sep 2027
Valid To 31 Aug 2033

Module Aims

The main aims of the module are: 

  • To develop advanced understanding of the cellular and molecular mechanisms underlying human disease and critically relate these processes to contemporary diagnostic technologies and clinical science practice. 

  • To enhance students’ ability to critically evaluate biomedical literature and interpret complex biomedical data, with a focus on assessing scientific validity, clinical relevance, and methodological quality. 

  • To foster evidence-based thinking by enabling students to appraise the clinical and scientific significance of biomedical investigations and their role in driving improvements in diagnostics, healthcare practice, and future biomedical innovation. 

Content Summary

This module provides advanced study of the cellular and molecular mechanisms that underpin human disease, linking these concepts to modern diagnostic technologies and clinical laboratory practice. You will explore how changes in cellular signalling, gene expression and molecular pathways contribute to disease development and how this knowledge is applied within contemporary biomedical diagnostics. 

You will critically evaluate biomedical investigations using current scientific literature and real-world datasets, developing your ability to assess research quality, interpret complex biomedical data and evaluate clinical relevance. The module places strong emphasis on evidence-based practice and the role of research in shaping diagnostic decision-making and future innovations in biomedical science. 

As part of the MSc Biomedical Science programme, this module strengthens your analytical, research and problem-solving skills while bridging theoretical molecular biology with applied clinical diagnostics. You will develop confidence in scientific reasoning, critical thinking and the independent evaluation of emerging biomedical technologies. 

The module is designed to prepare you for roles in clinical laboratories, research environments and translational healthcare, while also supporting progression to doctoral study or research-focused careers. Overall, it will help you develop the advanced scientific literacy, diagnostic insight and translational understanding needed for modern biomedical practice in rapidly evolving healthcare settings.

Learning and Teaching Methods

Activity Type Hours
Workshops and Case studies 56
Guided study 10.5
Self-directed study 173.5
Summative assessments 60
Total Hours Selected 300

Learning Outcomes

# Learning Outcome
LO1 Demonstrate advanced knowledge and critical understanding of the cellular and molecular mechanisms of disease and its relevance to diagnostic technologies and clinical science
LO2 Critically evaluate the clinical and scientific significance of biomedical investigations in scientific literature and biomedical data and its contribution to evidence-based practice and future innovations

Module Requisites

N/A

Assessment Criteria

Assessment Category Assessment Type Description Duration Word Count Weight (%) Best of? Pass Mark
Asynchronous Assessment Literature/book/paper review Individual Online AI Level 4: This assessment enables students to engage deeply with current biomedical research, critically analyse methodologies, interpret complex datasets and evaluate the translational significance of emerging evidence within disease diagnostics and clinical science. 0 3000 50 No 50
Synchronous Onsite Assessment  Classroom Test - Time Constrained (Onsite)  Individual: Complementary assessment because it assesses students’ breadth and depth of understanding of the cellular and molecular mechanisms underpinning disease processes and diagnostic technologies 180 N/A 50 No 50

Assessment Matrix

Assessment Type Learning Outcomes
LO1 LO2
Literature/book/paper review ✔ ✔
Classroom Test - Time Constrained (Onsite)  ✔ ✘

Reading List

Books 

Biomedical Translational Research: From Disease Diagnosis to Treatment 

Molecular Pathology (2nd edition) Edited by William B Coleman and Gregory J Tsongalis (2028) 

Biotechnology Applied to Inflammatory Diseases: Cellular Mechanisms and Nanomedicine (2023) Editors Daniele Ribeiro de Araujo, Marcela Carneiro-Ramos 

Advances in Medical Imaging, Detection and Diagnosis Editors G.S. Bawa et al. 

Journals 

Nature Reviews Molecular Cell Biology 

The Lancet 

BMJ 

Disease Models and Mechanisms