BI2S208 - Cellular Pathology & Disease Processes 01 Sep 2023 - 31 Aug 2028 | Version 2

Associated Module Information

Module Code: BI2S208
Module Title: Cellular Pathology & Disease Processes
Faculty: Faculty of Computing, Engineering and Science
Faculty Group: Applied Sciences
Faculty Sub Group: Biological Sciences
Module Leader: Sioned Owen
Module Team: Martin Powell, Lewis Fall, Josephine Bradley, Aled Bryant, Cerith Jones
First Intended Intake: SEP 2027 Final Year of Intake: 2027
Date Closed:
Credit Value: 20 Credit Level: 5
Language: English
Percentage of Module Taught in Welsh: 0
Equivalent Module:
HECOS codes: 100274 - pathology 100540 - cellular pathology 100912 - blood sciences
HECOS Code Weighting: 20 60 20

Document Version Information

Version 2
Valid From 01 Sep 2023
Valid To 31 Aug 2028

Module Aims

On successful completion students will have an understanding of the pathological changes associated with disease processes at molecular, cellular and tissue level and the impact this has on cellular and organ structure and function.

Using their understanding of the molecular and cellular changes occurring in various disease states and this impacts and informs diagnostic test and treatment options and future research directions. This will require the student to review and summarise research techniques and approaches and understand how this informs knowledge of pathological states.

The module is delivered using a range of lectures, practical classes and case based examples student will be able to understand how this knowledge also relates to a clinical setting.

In engaging with the module, students will fully achieve the following level appropriate behaviour domains of the USW Graduate attributes:-

Commerical awareness: Behaviour domain 1

Communication: Behaviour domains 1 & 2

Innovation and enterprise: Behaviour domains 1,2 &3

Project management: Behaviour domain 2

Digital literacy: Behaviour domain 3

The capabilities associated with these behaviours are found in the graduate attributes listed at the end of the descriptor.

Content Summary

Topics covering cellular pathology and disease states will include but are not limited to:-

Cellular pathology mechanisms including cell injury, wound healing, cellular communication and cell adaptions. Cellular changes to growth and differentiation and how this relates to tumour formation.

Immune system, inflammation and associated disorders.

Neurology: The process that occurs during acute brain injury and the pathogenesis of neurodegeneration and demyelinating diseases.

Reproductive biology: Disorders of pregnancy

Haematology: Basics of haematopoiesis, haemostasis and bleeding and thrombotic disorders. Haematological malignancies and anaemia. History of blood transfusions and its complications.

Learning and Teaching Methods

Activity Type Hours
Tutorial 48
Independent Study 70
Directed Study 68
Problem / challenge based learning 12
Total Hours Selected 198

Learning Outcomes

# Learning Outcome
LO1 Understand the microanatomy of different tissues in relation to normal function and pathology and to apply this knowledge and laboratory techniques to the critical appraisal of peer-reviewed scientific research
LO2 Explain the cellular and molecular processes associated with different disease states and to apply this knowledge to potential diagnostic and treatment options

Module Requisites

Code Title Requisite Type
MOD012896 Genetics and Evolution pre-requisite
MOD012893 Anatomy, Physiology, and Biochemistry pre-requisite
MOD012895 Diversity of Cellular Life pre-requisite
}

Assessment Criteria

Assessment Category Assessment Type Description Duration Word Count Weight (%) Best of? Pass Mark
Synchronous Onsite Oral Assessment Oral Assessment (Internally assessed, Onsite) 1 Viva Voce of application of knowledge. 15 N/A 60 No 40
Asynchronous Assessment Annotated Bibliography 1 Annotated bibliography of a primary research article 0 2000 40 No 40

Assessment Matrix

Assessment Type Learning Outcomes
LO1 LO2
Oral Assessment (Internally assessed, Onsite) 1
Annotated Bibliography 1

Reading List

Where possible students will be encouraged to engage with current scientific research articles rather than textbooks – examples of these will be available on the virtual learning environment and reviewed and updated annually.

A.L.Kierszenbaum, L.L.Tres. Histology And Cell Biology. An Introduction to Pathology. Third Edition. Elsevier Saunders

M.H. Ross, W. Pawlina. Histology, a Text and Atlas. Sixth Edition. Pub: Wolters Kluwer

https://www.osmosis.org/library/foundational-sciences/pathology

https://www.proteinatlas.org/humanproteome/pathology