7B023B - Regenerative Medicine: Mechanisms and Translation 01 Sep 2027 - 31 Aug 2033 | Version 0

Associated Module Information

Module Code: 7B023B
Module Title: Regenerative Medicine: Mechanisms and Translation
Faculty: Faculty of Computing, Engineering and Science
Faculty Group: Applied Science
Faculty Sub Group: Biology and Chemistry
Module Leader: Aled Bryant
Module Team: Martin Powell, Andrew Graham
First Intended Intake: SEP 2027 Final Year of Intake: 2032
Date Closed:
Credit Value: 30 Credit Level: 7
Language: English
Percentage of Module Taught in Welsh: 33
Equivalent Module:
HECOS codes: 100572 - tissue engineering and regenerative medicine
HECOS Code Weighting: 100

Document Version Information

Version 0
Valid From 01 Sep 2027
Valid To 31 Aug 2033

Module Aims

The main aims of the module are: 

  • To develop an advanced understanding of stem cell biology, including stem cell classification, self-renewal, differentiation, and the cellular and molecular mechanisms that regulate tissue development and repair. 

  • To develop critical knowledge of current and emerging regenerative medicine approaches, including stem cell therapies, tissue engineering, and gene-editing technologies, and their application in clinical and research settings. 

  • To enable students to evaluate the scientific, ethical, and regulatory challenges associated with translating regenerative medicine technologies from laboratory research to clinical practice. 

Content Summary

This module provides an advanced exploration of stem cell biology and regenerative medicine, linking fundamental cellular mechanisms to emerging clinical applications. You will develop a detailed understanding of stem cell classification, self-renewal, differentiation, and the molecular regulation of tissue development and repair. This knowledge will help you understand how biological processes can be applied and manipulated for therapeutic purposes. 

The module explores current and developing regenerative medicine approaches, including stem cell therapies, tissue engineering, organoid systems and gene-editing technologies. You will examine how these innovations are being translated into clinical practice to treat degenerative diseases, tissue damage and genetic disorders. 

A key feature of the module is its integration of scientific theory with translational and applied perspectives, encouraging interdisciplinary thinking across molecular biology, biotechnology and clinical science. You will critically evaluate the scientific evidence, clinical effectiveness and limitations of regenerative medicine approaches, while also considering the ethical, societal and regulatory issues associated with their development and use. 

The module supports the development of advanced analytical, evaluative and research skills relevant to careers in biomedical research, clinical laboratories and biotechnology, while also preparing you for doctoral study in this rapidly evolving field.

Learning and Teaching Methods

Activity Type Hours
Workshops and practicals / challenge-based learning 56
Guided study (including 10.5 digital learning) 15
Self directed study 139
Formative assessment 30
Summative assessment 60
Total Hours Selected 300

Learning Outcomes

# Learning Outcome
LO1 Critically evaluate the biological principles and clinical applications of stem cell biology in regenerative medicine, including stem cell sources, differentiation pathways, niche regulation, and the molecular mechanisms underpinning tissue repair and regeneration.
LO2 Analyse and critically appraise current and emerging regenerative medicine strategies, including cell-based therapies, tissue engineering, and gene editing approaches, with consideration of translational challenges relating to safety, efficacy, ethical issues, clinical trial governance, Good Clinical Practice, and regulatory frameworks in clinical application and healthcare practice.

Module Requisites

Code Title Requisite Type
MOD014234 Cellular and Molecular Basis of Disease pre-requisite
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Assessment Criteria

Assessment Category Assessment Type Description Duration Word Count Weight (%) Best of? Pass Mark
Synchronous Onsite Oral Assessment Clinical Viva (Onsite) Individual: The viva defence further enhances authenticity by assessing students’ ability to justify and defend scientific recommendations under critical questioning, reflecting professional and interdisciplinary biomedical environments. Students must articulate evidence-based arguments, evaluate uncertainties and respond to challenge, demonstrating confidence, leadership, communication and advanced critical thinking 23 N/A 25 No 50
Asynchronous Assessment Case study Individual Online: The written report directly aligns with the first learning outcome by requiring students to critically evaluate stem cell biology, differentiation pathways and regenerative mechanisms within a clinically relevant scenario. 0 4500 75 No 50

Assessment Matrix

Assessment Type Learning Outcomes
LO1 LO2
Clinical Viva (Onsite) ✔ ✔
Case study ✔ ✔

Reading List

Books 

Regenerative Medicine – Protocol to Patient: Stem Cell Science and Technology Editor Gustav Steinhoff 

Journals 

Stem Cell Research and Therapy 

Cell Stem Cell 

Nature Reviews Molecular Cell Biology 

Regenerative Medicine